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CAAT Academy Course Type: Short courses (CPD) Start Date: To be announced
Duration: Full time - 2 Days Fees/total cost: EUR 590.00
Prediction of hepatotoxicity remains a challenge nowadays. Focusing on the mechanisms instead of relying on generic readouts (cell death free radicals...) is the way to go and implies using cell systems that are shown to have intact molecular pathways for a given mechanism. In parallel the progress in cell biology that deliver new models derived from the iPSC or new culture methods such as 3D or flow through devices make available many new assay systems. And the question is: Which is the relevant system for addressing a certain hepatotoxicity project? The session will cover those new systems that are commercially ...

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CAAT Academy Course Type: Short courses (CPD) Start Date: To be announced
Duration: Full time - 2 Days Fees/total cost: EUR 590.00
The program will cover practical use of respiratory in vitro 3D tissues and exposure devices to evaluate acute and repeated dose inhalation toxicity. To mimic systemic context, interconnection strategies of lung tissues will be presented. Activities will be split into four sections: • In vitro models and tests for inhalation toxicity assessment (human and rodent 3D models): Epithelix • In vitro models and assays to detect lung carcinogenesis: OncoTheis • Exposure strategies and devices for testing at the Air-Liquid. Interface: Vitrocell • Interconnection of respiratory tissues and online detection of their integrity: Hepia Final Agenda available here. 

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CAAT Academy Course Type: Short courses (CPD) Start Date: To be announced
Duration: Full time - 2 Days Fees/total cost: EUR 590.00
This toxicological course with focus on hands-on training will, thanks to a number of companies engaged in the field of 3Rs, guide you through some of the validated OECD guidelines on local toxicity testing: 3 different skin models will be used to show practical applicability either in the field of skin irritation (EpiSkin, OECD TG 439), skin sensitization (Immunosearch) or skin permeability (Eurosafe). An eye irritation model as developed by Mattek will be used to demonstrate its applicability for eye irritation detection (OECD TG 492).

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CAAT Academy Course Type: Short courses (CPD) Start Date: To be announced
Duration: Full time - 2 Days Fees/total cost: EUR 590.00
The goal of this workshop is to make attending scientists familiar with the design and conduct of typical in vitro experiments that are performed to profile the hepatic disposition characteristics of new drug candidates and/or xenobiotics. Focus will be on sound protocols for generating high quality in vitro data that can subsequently be used as input in physiologically-based pharmacokinetic (PBPK) models. Importantly, the workshop program will also cover adequate in vitro data processing as required before input into PBPK. Combination of data from various in vitro models will also aid in getting novel and mechanistic insights in drug disposition. For ...

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CAAT Academy Course Type: Short courses (CPD) Start Date: To be announced
Duration: Full time - 2 Days Fees/total cost: EUR 590.00
This two-days training intends to cover the most robust and emerging models as well as best practices when it comes to build a read-across justification for regulatory purposes. It is co-organised by CAAT-Academy and ecopa/ssct as a satellite event of the conference. Participants will learn how to integrate data and run them under CEFIC-LRI AMBITtool (Nina Jeliazkova, IdeaConsult), ToxRead (Emilio Benfennati, Mario Negri), Toxtrack, (Costanza Rovida, EU-Toxrisk21, CAAT-Europe), and REACH-Across (Anne Bonhoff, UL). Last but not least participants will be walked through into a case-study specific endpoint (tba) as well as the integration of read-across dataset under IUCLID 6 (Monica ...

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CAAT Academy Course Type: Short courses (CPD) Start Date: To be announced
Duration: Full time - 2 Days Fees/total cost: EUR 590.00
In Skin Sensitization, more emphasis will be put on skin sensitization models such as h-CLAT (OECD TG 442E), DPRA (OECD TG 442C) or LuSens. The participants will also perform the IL/18 epiderm for identification and classification of skin sensitizing chemicals (MatTek) as well as the GARD skin sensitization test that detects  potency (Senzagen). Final Agenda available here. 

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CAAT Academy Course Type: Short courses (CPD) Start Date: To be announced
Duration: Full time - 2 Days Fees/total cost: EUR 590.00
This 2-days training will give a comprehensive overview of the most relevant and robust 2D and 3D kidney cell culture models and in vitro applications for the assessment of kidney-associated cytotoxicity. Topics that will be covered during the course include: 1) Regulatory aspects 2) In vitro models and techniques that are valuable to measure toxicity: • Normal, hTERT immortalized and iPSC-derived kidney cells • 2D and 3D kidney culture (high density transwell culture, spheroids, microfluidic chips) • Toxicity assessment using e.g. multi-well plates and Raman microspectroscopy with deep insight into read-out and interpretation of data

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Country: Germany (DE) Type: University
CAAT Academy
CAAT Academy is an extension of a joint venture of Johns Hopkins University Center for Alternatives to Animal Testing (CAAT) and CAAT-Europe (University of Konstanz). CAAT Academy is not-for profit and connects ...

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Country: United Kingdom (GB/UK) Type: Non-University Telephone: +44 (0)131 623 1938
European Centre of Technology
The European Centre of Technology works to promote best practice in management, finance and engineering education through training and qualifications with universities worldwide and publications and conferences with the United ...

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Country: United States (US) Type: Non-University Telephone: 0018587931295
Speid & Associates, Inc.
Speid & Associates, Inc. provides expert services in regulatory affairs and drug development for the pharmaceutical industry. As a way of giving something back to society, Dr. Speid runs a ...

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Country: Germany (DE) Type: Non-University
TÜV SÜD
TÜV SÜD is a technical service provider of testing, product certification, auditing, systems certification, training and knowledge services, based in Munich.

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TÜV SÜD Course Type: Short courses (CPD) Start Date: To be announced
Duration: Full time - 5 Days Fees/total cost: EUR 2,093.21
Customer focus and productivity are key elements of business success. Their optimization is seen as an indispensable prerequisite for a successful appearance on the national and international market. This is precisely where quality management comes in: flawless products and services form the basis for customer satisfaction. Targeted planned and continuously improved activities taking into account the dynamic environment increase the productivity of the organization considerably.With the course Quality Management Specialist, you will succeed in a universal entry into quality management. They are thus able to participate in the development and maintenance of a process-oriented management system and are familiar with the operational components of ...

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TÜV SÜD Course Type: Short courses (CPD) Start Date: To be announced
Duration: Full time - 1 Day Fees/total cost: EUR 529.55
  The quality and reliability requirements for products and services are increasing. Customer expectations are becoming more demanding, while competitive pressure is increasing in parallel. At the same time, companies are required to use current processes and technologies. Only those who quickly and reliably implement new requirements in such an environment can assert themselves. Ensuring competitiveness is becoming ever more important, especially in these areas, and a quality management system is becoming increasingly important. The standard series DIN EN ISO 9000 ff. is valid as a recognized standard in Germany and worldwide.  A key challenge in implementing an effective quality management system is to effectively ...

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